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OCR: Resident and Staff Physician Patient Education Chart The Function of IgG in an Allergic Reaction IgG Plasma Cell Some plasma cells produce another type of antibody (IgG) when exposed to an allergen. IgG does not stick to mast cells or basophils, but it does compete with IgE for attachment to the allergen. The release of histamine is avoided. Reprinted with permission from Resident and Staff Physician (c) 1991-92, 1993 by Romaine Pierson Publishers, Inc.